Quick answer: Yellow pothos leaves can reflect overwatering, drought, low light, root damage, pests, temperature stress or ordinary leaf aging. The most useful next step is to assess the mix and nearby foliage rather than immediately adding water or fertilizer.
Single old leaf or widespread yellowing?
One aging leaf near the base of a healthy growing vine can be normal. Several yellowing leaves together with soggy mix, wilting or stem softness deserve closer inspection. Rapid yellowing after a window move or cold draft points to an environmental change. A pattern affecting new foliage is different from occasional mature-leaf loss.

Check whether roots are wet or dry
Lift the pot and feel below the soil surface. If it is very light and dry, water thoroughly and drain. If it is heavy and wet, avoid watering again, ensure drainage and examine roots if decline continues. Prolonged saturation reduces oxygen and can damage roots. These opposite water stresses can both result in yellow leaves, so symptoms alone are not enough.

Assess light and temperature
Pothos tolerates some shade but can grow slowly in very dim spaces. Gradual movement into bright filtered light often helps healthy new growth. Harsh direct midday sun can yellow and scorch leaf tissue. Keep tropical vines away from freezing windows, heater blasts and repeated strong air-conditioning drafts.
Inspect insects and fertilizer history
Small attached scale, mealybug wax, mites or thrips can damage foliage. Check the undersides and vine nodes before choosing a control. If the root ball is healthy but growth has depleted nutrients over a long period, a complete houseplant feed may help; however, fertilizer salts can also burn roots when heavily applied. Do not feed a plant solely because its leaves are yellow.

Recovery checklist
Record changes, check root-zone moisture, inspect insects, confirm the pot drains and gradually optimize light. Remove fully dead leaves when convenient but keep mostly green foliage. Watch whether new leaves remain healthy; already yellowed mature leaves usually do not recover normal color.
Frequently asked questions
Can yellow pothos leaves turn green again?
Typically not once the leaf has yellowed substantially.
Should I water immediately?
Only after checking the mix; yellowing also happens from saturated roots.

